Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Mixed-methods Study of How to Improve Primary-secondary Transitions in England: Combining Academic Research with Policy and Practice Consultation.

Educational psychology review·2026
Same author

Perceptions of friendship, peers and influence on adolescent smoking according to tobacco control context: a systematic review and meta-ethnography of qualitative research.

BMC public health·2023
Same author

Resource Allocation in a National Dental Service Using Program Budgeting Marginal Analysis.

JDR clinical and translational research·2021
Same author

Pre-Flight Calibration of the Mars 2020 Rover Mastcam Zoom (Mastcam-Z) Multispectral, Stereoscopic Imager.

Space science reviews·2021
Same author

Crustal seismic velocity responds to a magmatic intrusion and seasonal loading in Iceland's Northern Volcanic Zone.

Science advances·2019
Same author

The impact of an epilepsy nurse competency framework on the costs of supporting adults with epilepsy and intellectual disability: findings from the EpAID study.

Journal of intellectual disability research : JIDR·2019

Related Experiment Videos

Secondary glaucoma after paediatric cataract surgery.

B N Swamy1, F Billson, F Martin

  • 1MBBS FRANZCO, Save Sight Institute, University of Sydney, Discipline of Clinical Ophthalmology and Eye Health, Campus of Sydney Eye Hospital, GPO Box 4337 Sydney NSW 2001, Australia.

The British Journal of Ophthalmology
|May 4, 2007
PubMed
Summary

Secondary glaucoma is a significant risk following congenital cataract surgery, affecting 15.4% of patients. Early surgery (under 9 months) and microcornea are key risk factors, necessitating lifelong patient surveillance.

Related Experiment Videos

Area of Science:

  • Ophthalmology
  • Pediatric Surgery
  • Glaucoma Research

Background:

  • Congenital cataracts are a leading cause of childhood visual impairment.
  • Cataract surgery in children can lead to various complications, including secondary glaucoma.
  • Identifying risk factors is crucial for proactive management and improved patient outcomes.

Purpose of the Study:

  • To determine the prevalence of secondary glaucoma after congenital cataract surgery.
  • To identify risk factors associated with the development of secondary glaucoma in pediatric patients.
  • To inform long-term surveillance strategies for children undergoing cataract surgery.

Main Methods:

  • Retrospective case series of 283 patients (423 eyes) who underwent congenital cataract surgery.
  • Analysis of medical records from 1985-2005 at a major children's hospital.
  • Statistical analysis using Kaplan-Meier survival and Multivariate Cox hazards regression to identify risk factors.

Main Results:

  • Secondary glaucoma developed in 15.4% of patients.
  • Key predictors for glaucoma included younger age at surgery (less than 9 months) and microcornea.
  • Glaucoma onset ranged from 2 weeks to over 16 years post-surgery, with a mean follow-up of 6.3 years.

Conclusions:

  • Secondary glaucoma is a significant and potentially delayed complication of congenital cataract surgery.
  • Lifelong ophthalmological surveillance is essential for patients operated on for congenital cataracts.
  • Early surgical intervention and presence of microcornea increase the risk, requiring vigilant monitoring.