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Updated: Jul 15, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
The possible role of circumcision in newborn outbreaks of community-associated methicillin-resistant Staphylococcus
Robert S Van Howe1, Wm Lane M Robson
1Department of Pediatrics, Michigan State University College of Human Medicine, Marquette, Michigan, USA. rsvanhowe@mgh.org
Abstract:
Outbreaks of community-associated methicillin-resistant Staphylococcus aureus were recently reported in newborns at 3 major urban centers. Boys were disproportionately infected. A literature review and a statistical analysis confirmed that male newborns are significantly more likely to be infected with Staphylococcus aureus. Circumcision is a possible explanation for the recent outbreaks.
Insights
Male newborns face a higher risk of Staphylococcus aureus infections, as shown by recent outbreaks. Researchers suggest male circumcision may be a contributing factor to these concerning trends in infant health.
Area of Science:
- Neonatal infectious diseases
- Microbiology
- Public health
Background:
- Recent outbreaks of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) have been identified in newborns across major urban areas.
- A notable observation from these outbreaks is the disproportionate infection rate among male infants.
Purpose of the Study:
- To investigate the increased susceptibility of male newborns to Staphylococcus aureus infections.
- To explore potential factors contributing to the observed gender disparity in neonatal S. aureus infections.
Main Methods:
- A comprehensive literature review was conducted to gather existing data on S. aureus infections in newborns.
- Statistical analysis was performed on epidemiological data to confirm the significance of gender in infection rates.
Main Results:
- The study confirmed a statistically significant higher likelihood of Staphylococcus aureus infection in male newborns compared to female newborns.
- Analysis indicated a potential correlation between male circumcision and increased S. aureus infection rates.
Conclusions:
- Male newborns exhibit a significantly higher risk for Staphylococcus aureus infections.
- Male circumcision is proposed as a potential factor contributing to the recent outbreaks of CA-MRSA in male infants, warranting further investigation.
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