Related Experiment Video
Updated: Jul 15, 2026

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
Epidemiology of childhood meningitis in Kuwait
Entesar H Husain1, Faisal Al-Shawaf, Esmaeel Bahbahani
1Department of Pediatrics, Faculty of Medicine Safat, Kuwait. entesar@qualitynet.net
Background:
Haemophilus influenzae type b (Hib) conjugate vaccine was introduced as part of childhood routine immunization in Kuwait in 1996. The aim of this study is to describe the epidemiological, microbiological, and clinical features of meningitis among children in Kuwait from 2001 to 2003.
Material/Methods:
A multicenter retrospective review of clinical records of otherwise healthy children hospitalized with a diagnosis of meningitis.
Results:
A total of 172 children had a diagnosis of meningitis and had lumbar puncture during the study period. The median age was 8 months. The majority (67%) of the patients were less than 5 yeas of age. Eighty-six (50%) of the patients had aseptic meningitis and 19 (11%) had partially treated meningitis. The remaining 67 (39%) were diagnosed with bacterial meningitis. The underlying organisms were: Neisseria meningitidis (49%), group B streptococci (18%), Streptococcus pneumoniae (18%), Mycobacterium tuberculosis (6%), Gram-negative organisms (6%), and Haemophilus species (1.5%). Twelve percent required admission to the intensive care unit. At the time of discharge from the hospital, 9% had neurological sequelae, the majority of which were in patients who had S. pneumoniae meningitis. Two patients died during the study period.
Conclusions:
N. meningitidis is the leading bacterial agent of bacterial meningitis in Kuwait. S. pneumoniae is responsible for the majority of neurological sequelae of bacterial meningitis in infants and young children. The results of this study can be used in future public health planning in the context of the newly available vaccines.
Insights
Neisseria meningitidis caused most bacterial meningitis cases in Kuwaiti children. Streptococcus pneumoniae led to the most neurological issues, highlighting the need for targeted public health strategies and new vaccines.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Routine childhood immunization in Kuwait began with Haemophilus influenzae type b (Hib) conjugate vaccine in 1996.
- This study examines meningitis trends in children from 2001 to 2003.
Purpose of the Study:
- To describe the epidemiological, microbiological, and clinical characteristics of pediatric meningitis in Kuwait.
- To inform public health planning and vaccine strategies.
Main Methods:
- Multicenter retrospective review of clinical records.
- Inclusion criteria: otherwise healthy children hospitalized with meningitis diagnosis.
- Lumbar puncture performed for diagnosis.
Main Results:
- 172 children diagnosed with meningitis; median age 8 months, 67% under 5 years.
- Bacterial meningitis in 39% of cases, with Neisseria meningitidis (49%) as the leading cause.
- Streptococcus pneumoniae caused most neurological sequelae (9% overall); 12% ICU admission, 2 deaths.
Conclusions:
- Neisseria meningitidis is the primary bacterial cause of meningitis in Kuwait.
- Streptococcus pneumoniae is linked to the majority of neurological sequelae in young children.
- Findings support public health planning and the integration of new vaccine data.
Related Concept Videos
Bacterial Meningitis I: Introduction
Viral Meningitis
Bacterial Meningitis
Encephalitis l: Introduction
Bacterial Meningitis II: Pathophysiology
Cryptococcal Meningitis
