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Liquid versus gel handrub formulation: a prospective intervention study.

Ousmane Traore1, Stéphane Hugonnet, Jann Lübbe

  • 1Infection Control Programme, University of Geneva Hospitals, 24 Rue Micheli-du-Crest, 1211 Geneva 14, Switzerland. otraore@chu-clermontferrand.fr

Critical Care (London, England)
|May 5, 2007
PubMed
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Improving healthcare worker hand hygiene compliance is vital. An alcohol-based gel handrub, easily accessible, significantly boosts compliance and skin health.

Area of Science:

  • Infection Prevention and Control
  • Occupational Health
  • Public Health

Background:

  • Health care-associated infections (HAIs) are a significant concern, with hand hygiene being a primary preventive measure.
  • Despite its importance, healthcare worker (HCW) compliance with hand hygiene protocols remains suboptimal.
  • Alcohol-based handrubs are the global standard, but their successful implementation requires addressing product acceptability and system changes.

Purpose of the Study:

  • To compare the impact of liquid versus gel alcohol-based handrub formulations on HCW compliance.
  • To assess product acceptability and skin tolerance among HCWs.
  • To identify factors associated with improved hand hygiene compliance.

Main Methods:

  • A prospective intervention study was conducted in a medical intensive care unit with 102 HCWs.

Related Experiment Videos

  • Compliance was monitored by a single observer, with data collected across two phases (liquid vs. gel formulation).
  • Skin tolerance and acceptability were evaluated using subjective/objective scoring, questionnaires, and biometric measurements; logistic regression analyzed compliance predictors.

    • Main Results:

    • Overall hand hygiene compliance varied by profession (nurses: 39.1%, physicians: 27.1%, nursing assistants: 31.1%, others: 13.9%).
    • Easy access to handrub significantly improved compliance (35.3% vs. 50.6%).
    • Gel formulation, nurse status, morning shifts, and pocket availability of handrub were independently linked to higher compliance; immediate accessibility was the strongest predictor. The gel formulation showed better skin tolerance.

    Conclusions:

    • Facilitated access to alcohol-based gel handrub formulations enhances HCW compliance with hand hygiene practices.
    • The gel formulation demonstrated superior skin condition outcomes compared to the liquid formulation.
    • Optimizing handrub accessibility and formulation is key to improving infection control in healthcare settings.