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Updated: May 30, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
Published on: August 13, 2017
Massive bone defects of the upper limb: reconstruction by vascularized bone transfer
Michael B Wood1, Allen T Bishop
1Department of Orthopedic Surgery, Division of Hand Surgery, Mayo Clinic College of Medicine, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA.
Abstract:
Vascularized bone transfer is increasingly recognized as a very useful and versatile technique for reconstructing massive bone defects in the upper limb or in patients with especially challenging conditions, such as infected nonunions and nonunions associated with radionecrosis of bone. It is especially indicated for the humerus and shoulder region with more selected applications in the forearm or wrist. Although technically challenging, the outcomes of this procedure justify consideration along with alternative methods for major reconstructions of the upper limb.

