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Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
Published on: August 13, 2017
Massive bone defects of the upper limb: reconstruction by vascularized bone transfer
Michael B Wood1, Allen T Bishop
1Department of Orthopedic Surgery, Division of Hand Surgery, Mayo Clinic College of Medicine, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA.
Hand Clinics
|May 5, 2007
Summary
Vascularized bone transfer effectively reconstructs large upper limb bone defects, even in complex cases like infected nonunions. This versatile technique, particularly for the humerus and shoulder, offers a viable option for challenging reconstructions.
Area of Science:
- Orthopedic Surgery
- Reconstructive Surgery
- Bone Grafting
Background:
- Massive bone defects in the upper limb present significant reconstructive challenges.
- Infected nonunions and radionecrosis-associated nonunions require advanced treatment modalities.
- Vascularized bone transfer is an evolving technique for complex bone reconstruction.
Purpose of the Study:
- To highlight the utility and versatility of vascularized bone transfer for upper limb reconstruction.
- To discuss the indications and outcomes of this procedure in challenging clinical scenarios.
- To compare vascularized bone transfer with alternative reconstructive methods.
Main Methods:
- Review of clinical applications and outcomes of vascularized bone transfer in the upper limb.
- Analysis of cases involving massive bone defects, infected nonunions, and radionecrosis.
- Evaluation of surgical technique and patient selection criteria.
Main Results:
- Vascularized bone transfer demonstrates significant success in reconstructing large bone defects, particularly in the humerus and shoulder.
- The procedure is a valuable option for managing infected nonunions and nonunions secondary to radionecrosis.
- While technically demanding, outcomes support its consideration for major upper limb reconstructions.
Conclusions:
- Vascularized bone transfer is a highly effective and versatile technique for complex upper limb bone reconstructions.
- Its application is particularly beneficial for the humerus and shoulder, offering solutions for challenging nonunions.
- The procedure warrants consideration alongside other reconstructive options for severe bone defects.

