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Subtypes of pediatric delirium: a treatment algorithm.
Niranjan S Karnik1, Shashank V Joshi, Caroline Paterno
1Division of Child and Adolescent Psychiatry, Stanford Univ. School of Medicine, Lucile Salter Pasckard Children's Hospital, Palo Alto, CA 94305, USA. nkarnik@stanford.edu
Psychosomatics
|May 5, 2007
Summary
Pediatric delirium subtypes, hyperactive and hypoactive/mixed, are explored in two cases. Treatment responses to haloperidol and risperidone varied by subtype, informing a new pediatric delirium management algorithm.
Area of Science:
- Pediatric critical care medicine
- Neuroscience
- Pharmacology
Background:
- Delirium in hospitalized adults is classified into hyperactive, hypoactive, and mixed subtypes.
- The applicability of these subtypes to pediatric populations requires further investigation.
Observation:
- This case report details two pediatric patients exhibiting delirium, illustrating hyperactive and hypoactive/mixed subtypes.
- Distinct responses to haloperidol and risperidone were observed across different delirium subtypes.
Findings:
- Pharmacological interventions like haloperidol and risperidone demonstrate differential efficacy based on pediatric delirium subtype.
- The study proposes neurochemical pathways underlying these varied treatment responses.
Implications:
- The findings support the classification of pediatric delirium into distinct subtypes.
- A novel treatment algorithm for pediatric delirium is presented, guiding clinical management based on subtype and pharmacological response.
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