Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Topical heparin: new observations.

M R Cesarone1, G Belcaro, S Errichi

  • 1Irvine2 Vascular Lab and Physiology, Department of Biomedical Sciences, Chieti-Pescara University, Faculty of Motory Sciences, L'Aquila University, San Valentino, Italy.

Angiology
|May 5, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stop antibiotics when you feel better? Opportunities, challenges and research directions.

JAC-antimicrobial resistance·2024
Same author

Autonomic cardiac function in children and adolescents with long COVID: a case-controlled study.

European journal of pediatrics·2024
Same author

Outer retina dysfunction and choriocapillaris impairment in type 1 diabetes.

Scientific reports·2021
Same author

Pycnogenol® Supplementation Prevents Recurrent Urinary Tract Infections/Inflammation and Interstitial Cystitis.

Evidence-based complementary and alternative medicine : eCAM·2021
Same author

Prenatal exposure to different diets influences programming of glucose and insulin metabolism in dairy ewes.

Journal of dairy science·2020
Same author

Interaction study between antiplatelet agents, anticoagulants, thyroid replacement therapy and a bioavailable formulation of curcumin (Meriva®).

European review for medical and pharmacological sciences·2018
Same journal

Refining Phenotype-Based Interpretation of SGLT2 Inhibitors After AMI Without Heart Failure.

Angiology·2026
Same journal

Response to: "Integrating Noninvasive Liver Indices into Risk Stratification of Myocardial Infarction With Non-Obstructive Coronary Arteries".

Angiology·2026
Same journal

Response to: "Beyond Traditional Risk Markers: Is FIB-4 Sufficient in MINOCA?"

Angiology·2026
Same journal

Letter: Further Considerations on the Clinical Use of the Scottish Inflammatory Prognostic Score in STEMI No-Reflow Prediction.

Angiology·2026
Same journal

Contextualizing Remodeling Endpoints in Endovascular Treatment for Symptomatic SISMAD.

Angiology·2026
Same journal

<i>Response to the Letter to the Editor</i>: "Effect of Invasive Hemodynamic Monitoring on the Outcomes of Cardiogenic Shock in Patients With Acute Myocardial Infarction".

Angiology·2026
See all related articles

Local heparin demonstrates anticoagulant, microcirculatory, and drug delivery benefits for skin applications. Further research is needed to explore its potential in treating superficial vein thrombosis (SVT) and enhancing transdermal drug efficacy.

Area of Science:

  • Dermatology
  • Pharmacology
  • Thrombosis Research

Background:

  • Topical heparin's skin effects require further investigation due to limited research.
  • Heparin exhibits anticoagulant, microcirculatory modulation, and enhanced skin permeability properties.

Purpose of the Study:

  • To explore the local actions of heparin on the skin.
  • To evaluate the potential clinical applications of topical heparin, especially in liposomal formulations.
  • To examine new aspects in managing superficial vein thrombosis (SVT) with local heparin.

Main Methods:

  • Review of recent experimental studies on locally applied heparin.
  • Analysis of heparin's effects on skin penetration and local thrombi.
  • Consideration of new formulations and clinical observations.

Related Experiment Videos

Main Results:

  • Experimental studies confirm heparin's local skin effects, including penetration and action on thrombi.
  • Local heparin shows promise for enhanced drug delivery and microcirculation control.
  • New formulations suggest significant clinical applications for topical heparin.

Conclusions:

  • Local heparin administration offers multifaceted benefits for skin conditions.
  • Topical heparin, particularly liposomal formulations, holds potential for treating SVT and improving drug delivery.
  • Further clinical and experimental evaluation is warranted to fully realize heparin's dermatological applications.