Related Experiment Video
Updated: Jul 15, 2026

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
Published on: February 21, 2015
[Identification of the origin of marker chromosome by comparative genomic hybridization]
Lu Zhou1, Ling-Qian Wu, De-Sheng Liang
1National Laboratory of Medical Genetics of China, Xiangya Hospital, Central South University, Changsha, China.
Objective:
To identify the origin of the marker chromosome in a patient with chromosome aberration, and to provide the precise genetic diagnosis.
Methods:
Comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH) were performed to detect the known small marker chromosome in this patient.
Results:
The small marker chromosome originated from chromosome 13 pter->q12.
Conclusion:
CGH and FISH can be used to detect the small marker chromosome, which is convenient and quick in detecting the origin of small marker chromosome.
Related Concept Videos
Karyotyping
FISH - Fluorescent In-situ Hybridization

