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Monitoring the anaesthetic depth in children - an update
1Department of Anaesthesia & Pain Management, Royal Children's Hospital, Melbourne, Australia. andrew.davidson@rch.org.au
Insights
Electroencephalogram-derived devices can monitor anesthesia depth in children. While effective for older children, their performance is poorer in infants, with no single device proving superior.
Area of Science:
- Anesthesiology
- Neuroscience
- Pediatric Critical Care
Background:
- Electroencephalogram (EEG)-derived devices offer potential for monitoring anesthesia depth.
- Several commercial devices are available, utilizing EEG signals to assess the level of anesthesia.
Purpose of the Study:
- To review published studies on the use of EEG-derived devices for monitoring anesthesia depth in children.
- To assess device performance in observational and physiological studies and review outcome studies.
- To discuss the clinical utility, potential physiological issues, and methodological considerations.
Main Methods:
- Systematic review of published literature on EEG-derived anesthesia depth monitoring in pediatric populations.
- Analysis of physiological studies evaluating device performance against anesthetic agent doses.
- Examination of outcome studies assessing clinical impact, such as drug consumption and recovery time.
Main Results:
- Physiological studies indicate that bispectral index, entropy, Narcotrend index, cerebral state index, and A-line ARX index correlate with anesthetic agents in older children.
- Device performance is significantly reduced in infants.
- Some devices have shown potential to decrease anesthetic drug use and accelerate recovery in older children.
Conclusions:
- The bispectral index is the most studied, but no EEG-derived device demonstrates clear superiority.
- Emerging evidence supports the use of these devices in older children.
- Current evidence does not support the use of EEG-derived anesthesia depth monitoring in infants.
Purpose Of Review:
There are several commercially available electroencephalogram-derived devices for monitoring anaesthesia depth. This article reviews all published studies describing their use in children; first assessing studies of performance in measuring anaesthesia depth in observational, physiological studies and then describing relevant outcome studies. There is also a brief discussion of why they might be useful, what physiological problems may arise and what the reader should be wary of in the methodology of these studies. The subject is approached from a clinical perspective.
Recent Findings:
There are several physiological studies suggesting that for older children the bispectral index, entropy, Narcotrend index, cerebral state index and A-line ARX index all change with induction of anaesthesia, and have reasonable correlations with doses of anaesthetic agent. There is consistent evidence that the performances are substantially poorer in infants. Some of these devices have been demonstrated to reduce anaesthesia drug consumption and hasten recovery in older children.
Summary:
The bispectral index is the most widely studied, but at this stage there is no evidence to suggest any one device is substantially superior to any other. There may be a role emerging for their use in older children, but their use in infants cannot be supported.
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