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Updated: Jul 15, 2026
06:40
An In Vivo Mouse Model of Total Intravenous Anesthesia During Cancer Resection Surgery
Published on: June 8, 2021
Anaesthesia for cancer patients
Mujeebullah Rauf Arain1, Donal J Buggy
1Division of Anaesthesia, Intensive Care and Pain Medicine, Mater Misericordiae University Hospital, Dublin, Ireland.
Current Opinion in Anaesthesiology
|May 5, 2007
Summary
Anesthesia for cancer patients requires careful management due to organ system impacts from cancer and its treatments. Regional anesthesia techniques may reduce metastatic disease incidence in primary cancer surgery.
Area of Science:
- Oncology
- Anesthesiology
- Perioperative Medicine
Background:
- Cancer is a leading cause of death, necessitating anesthesia for surgical interventions and treatment complications.
- Cancer and its therapies significantly impact major organ systems, complicating perioperative care.
- Anesthetic management must address the pathophysiology of cancer, metastatic disease, and systemic treatments.
Purpose of the Study:
- To review the pathophysiology of cancer and its systemic effects relevant to anesthesia.
- To discuss anesthetic considerations for optimizing perioperative management in cancer patients.
- To explore the potential influence of anesthetic techniques on long-term cancer outcomes.
Main Methods:
- Review of cancer pathophysiology, metastatic disease, and systemic therapy effects on organ systems.
- Discussion of anesthetic considerations for perioperative management.
- Analysis of retrospective data suggesting links between anesthetic techniques and metastatic disease.
Main Results:
- Cancer and therapy negatively affect all major organ systems, impacting perioperative management.
- Retrospective studies indicate a correlation between regional anesthesia during primary cancer surgery and lower rates of metastatic disease.
Conclusions:
- Individualized assessment of cancer's impact on organ function is crucial for optimal perioperative care.
- The influence of anesthetic techniques on long-term cancer outcomes warrants further investigation.
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