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Updated: Jul 15, 2026
04:09
Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
[Limb salvage for the diabetic foot - disease management program]
1Abt. Diabetes, Stoffwechsel und Endokrinologie, Klinik Bavaria Kreischa, An der Wolfsschlucht 1-2, 01731 Kreischa. Matthias.Weck@klinik-bavaria.de
Hamostaseologie
|May 5, 2007
Summary
A structured disease management program for diabetic foot ulcers significantly reduced major amputations. This approach also demonstrated comparable ulcer healing rates to leading centers, improving patient outcomes.
Area of Science:
- Diabetology
- Vascular Surgery
- Wound Care
Context:
- Diabetic foot (DF) complications, including lower-extremity amputation (LEA), are a significant concern in diabetes management.
- A structured disease management program offers a potential strategy to mitigate these complications.
Purpose:
- To evaluate the effectiveness of a structured disease management program in reducing LEA among patients with DF.
- To assess ulcer healing rates and the impact of peripheral vascular disease within this patient cohort.
Summary:
- A prospective study followed 102 patients with new foot ulcers from 2000-2004, with a two-year follow-up.
- After two years, 50% of the original cohort achieved complete ulcer healing, and 7.8% underwent major amputation (MA).
- The program successfully achieved its primary objective of significantly reducing MA in DF patients.
Impact:
- The study demonstrates the efficacy of a structured disease management program in reducing major amputations for diabetic foot patients.
- Achieved ulcer healing rates are comparable to those reported by leading specialized centers.
- This approach offers a viable strategy for improving outcomes and limb salvage in diabetic patients with foot complications.
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