Two ellagic acid glycosides from Gleditsia sinensis Lam. with antifungal activity on Magnaporthe grisea
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Updated: Jul 15, 2026

Screening and Isolation of C-Glycoside-Cleaving Intestinal Bacteria
Published on: February 28, 2025
Ligang Zhou1, Duan Li, Weibo Jiang
1College of Agronomy and Biotechnology, China Agricultural University, Beijing 100094, China.
Abstract:
Two ellagic acid glycosides were isolated by bioassay-guided fractionation from the antimicrobial ethyl acetate fraction of the ethanol extract from Gleditsia sinensis spines, and identified as 3-O-methylellagic acid-4'-(5''-acetyl)-alpha-L-arabinofuranoside (1) and 3-O-methylellagic acid-4'-O-alpha-L-rhamnopyranoside (2). Both compounds were isolated from this plant species for the first time, and 1 is a new compound. The two compounds showed significant antifungal activity against the spore germination of rice blast fungus Magnaporthe grisea, with an IC(50) value of 13.56 microg mL(-1) for 1 and 16.14 microg mL(-1) for 2.
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