Diffuse malignant peritoneal mesothelioma in a 31-year-old patient--case report

M Prorocic1, M Vasiljevic, S Jankovic

  • 1University Clinic of Gynaecology and Obstetrics Narodni Front, Belgrade, Serbia.

Insights

A rare case of diffuse malignant peritoneal mesothelioma was diagnosed in a young woman presenting with pelvic pain and abdominal distension. Surgical intervention and chemotherapy led to a positive outcome, highlighting successful treatment strategies.

Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Diffuse malignant peritoneal mesothelioma is a rare and aggressive neoplasm.
  • Early diagnosis and comprehensive treatment are crucial for patient outcomes.

Observation:

  • A 31-year-old woman presented with pelvic pain and abdominal distension.
  • Pelvic ultrasonography revealed a cystic tumor mass.
  • Histopathological examination confirmed diffuse malignant peritoneal mesothelioma.

Findings:

  • The patient underwent diagnostic laparoscopy, followed by cytoreductive surgery including peritonectomy, omentectomy, and appendectomy.
  • Postoperative combined chemotherapy was administered.
  • The patient demonstrated a favorable response to treatment with no recurrence observed.

Implications:

  • This case highlights the importance of considering rare malignancies in young adults presenting with non-specific abdominal symptoms.
  • Multimodal treatment involving cytoreductive surgery and chemotherapy can achieve positive outcomes in diffuse malignant peritoneal mesothelioma.
  • Further research into optimal treatment protocols for this rare condition is warranted.