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Updated: Jul 15, 2026

Comprehensive Characterization of Tissue Mineralization in an Ex Vivo Model
Published on: September 27, 2024
[The evaluation of mineral crystallinity of mandibular bone tissue using electron paramagnetic resonance (EPR) in
Andrzej Wojtowicz1, Maciej Dijakiewicz, Barbara Wandzel
1Zakład Chirurgii Stomatologicznej ISAM w Warszawie. awojt@kcs.amwaw.edu.pl
Abstract:
Mineral crystallinity of bone tissue is subject to changes during one's development, as well as in many systemic diseases, especially renal osteodystrophy. The aim of the study was qualitative evaluation of the mandibular bone tissue in patients suffering from renal osteodytrophy, treated with renal-replacement therapy: hemo-dialysis or allogeneic kidney transplantation. The mineral crystallinity coefficient was evaluated using electron paramagnetic resonance (EPR) based on the observation that ionizing radiation induces paramagnetic centers in hydroxyapatites. The concentration of these centers was used to establish an indicator of crystallinity rate which is a measure of the crystallinity of tissue mineral. On the basis of these results, it is possible to widen the indications for implantological treatment in specific clinical cases.

