Jove
Visualize
Contact Us

Related Experiment Videos

Drugs in the elderly--more good than harm?

Keith Beard

    Expert Opinion on Drug Safety
    |May 8, 2007
    PubMed
    Summary
    This summary is machine-generated.

    Optimizing drug treatment for the elderly requires careful consideration of aging effects, polypharmacy, and evidence extrapolation. Addressing therapeutic biases and patient-centered concerns is crucial for safe and effective medication management in older adults.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Commentary: The balance between marketing and safety.

    BMJ (Clinical research ed.)·2008
    Same author

    Over the counter medicines: proceed with caution.

    BMJ (Clinical research ed.)·2008
    Same author

    European commission consultation on pharmacovigilance.

    Pharmacoepidemiology and drug safety·2007
    Same author

    Drug safety and the media.

    British journal of clinical pharmacology·2006
    Same author

    Regulating herbal medicines in the UK.

    BMJ (Clinical research ed.)·2005
    Same author

    Drug safety and regulation.

    BMJ (Clinical research ed.)·2005
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Gerontology
    • Clinical Pharmacology
    • Health Services Research

    Background:

    • The aging global population necessitates a focus on appropriate drug treatment for elderly individuals.
    • Elderly patients consume a significant proportion of all medicines, highlighting the importance of their specific needs.
    • Current drug treatment paradigms may not fully account for the complexities of aging and polypharmacy.

    Discussion:

    • Investigating the increased toxicity of drugs in the elderly, considering aging and polypharmacy.
    • Evaluating the applicability of evidence-based treatment options derived from younger populations to elderly patients.
    • Examining the inevitability and implications of polypharmacy in evidence-based geriatric pharmacotherapy.
    • Assessing potential professional biases or nihilism towards elderly patients' treatment, including the role of cost.

    Related Experiment Videos

  • Understanding the priorities and perspectives of elderly patients regarding their medication regimens.

    • Key Insights:

    • Drug toxicity may be exacerbated by aging and polypharmacy, requiring tailored safety assessments.
    • Evidence bases for younger populations may not be directly transferable to elderly patients.
    • Polypharmacy presents challenges and necessitates careful management within evidence-based geriatric care.
    • Professional attitudes and cost considerations can influence therapeutic decisions for older adults.
    • Patient-reported outcomes and preferences are essential for effective medication management in the elderly.

    Outlook:

    • Future research should focus on developing age-specific pharmacotherapy guidelines.
    • Interventions aimed at reducing polypharmacy and improving medication safety in the elderly are needed.
    • Promoting a patient-centered approach that incorporates the values and preferences of older adults is paramount.
    • Addressing professional biases and ensuring equitable access to effective treatments are critical.
    • Further studies are required to understand the long-term impact of evidence-based drug therapy on elderly populations.