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Applied potential tomography. Noninvasive method for measuring gastric emptying of a solid test meal
Y F Mangnall1, D D Kerrigan, A G Johnson
1Department of Surgery, University of Sheffield, Royal Hallamshire Hospital, England.
Digestive Diseases and Sciences
|December 1, 1991
Summary
Applied potential tomography (APT) accurately measures solid food gastric emptying, correlating well with scintigraphy when acid secretion is inhibited. This noninvasive method shows promise for gastric emptying studies.
Area of Science:
- Gastroenterology
- Medical Imaging
- Physiology
Background:
- Applied potential tomography (APT) is a novel, noninvasive, nonradioactive technique for assessing gastric emptying.
- Previous studies demonstrated APT's efficacy in measuring liquid gastric emptying, showing comparable results to scintigraphy and dye dilution methods.
Purpose of the Study:
- To validate the use of APT for measuring the gastric emptying of a solid meal (beefburger).
- To compare APT's solid meal gastric emptying measurements with those obtained simultaneously by scintigraphy.
Main Methods:
- Gastric emptying of a solid beefburger test meal was measured using both APT and scintigraphy.
- Measurements were conducted under conditions with and without acid secretion inhibition.
Main Results:
- A significant correlation was observed between APT and scintigraphy for key gastric emptying parameters (t½, amount emptied over time) when acid secretion was inhibited.
- Gastric emptying profiles generated by APT closely resembled those from scintigraphy under inhibited acid secretion conditions.
- No correlation was found between APT and scintigraphy for solid meal emptying when acid secretion was not inhibited.
Conclusions:
- Applied potential tomography (APT) is a validated method for assessing solid meal gastric emptying, particularly when gastric acid secretion is suppressed.
- APT offers a noninvasive, nonradioactive alternative to scintigraphy for solid gastric emptying studies, demonstrating good agreement under specific physiological conditions.