Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Portal hypertensive colopathy. A new entity.

S Naveau1, P Bedossa, T Poynard

  • 1Service d'Hépato-Gastroentérologie, Hôpital Antoine Béclère, Clamart, France.

Digestive Diseases and Sciences
|December 1, 1991
PubMed
Summary

Vascular ectasias (VE) in alcoholic cirrhotic patients are a complication of portal hypertension. These, along with rectal varices (RV), represent endoscopic findings of portal hypertensive colopathy, characterized by colonic mucosal capillary ectasia.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Morphometric Quantification of Steatosis and Fibrosis in Metabolic Liver Disease Associated With Type 2 Diabetes.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2025
Same author

Decision Tree for the Performance of Intraoperative Liver Biopsy During Bariatric Surgery.

Obesity surgery·2021
Same author

Diagnostic of hepatic fibrosis with the XL probe of the Fibroscan versus biopsies in patients candidates to bariatric surgery.

Clinical nutrition ESPEN·2020
Same author

The optimal indication for FiLaC<sup>®</sup> is high trans-sphincteric fistula-in-ano: a prospective cohort of 69 consecutive patients.

Techniques in coloproctology·2019
Same author

Evaluation of automated tool for two-dimensional fetal biometry.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2018
Same author

Impact of controlled attenuation parameter on detecting fibrosis using liver stiffness measurement.

Alimentary pharmacology & therapeutics·2018

Area of Science:

  • Gastroenterology
  • Hepatology
  • Pathology

Background:

  • Portal hypertension is a serious complication in alcoholic cirrhotic patients.
  • Colonic vascular ectasias (VE) and rectal varices (RV) are observed in these patients.
  • The underlying pathology of these vascular changes requires further elucidation.

Purpose of the Study:

  • To investigate the association between colonic VE and portal hypertension in alcoholic cirrhotic patients.
  • To determine if colonic VE and RV are endoscopic manifestations of a distinct entity, portal hypertensive colopathy.
  • To examine the histomorphometric characteristics of colonic mucosal capillaries in patients with and without these findings.

Main Methods:

  • A case-control study comparing alcoholic cirrhotic patients with colonic VE to matched controls.

Related Experiment Videos

  • Histomorphometric analysis of colonic mucosal capillaries.
  • Prevalence assessment of esophageal varices and history of bleeding.

    • Main Results:

    • Alcoholic cirrhotic patients with colonic VE showed a significantly higher prevalence of esophageal varices, larger esophageal varices, a history of bleeding, and rectal varices compared to controls.
    • The relative risk of colonic VE in patients with esophageal varices was 14.4.
    • Histomorphometric study revealed significantly higher mean vessel diameter and cross-sectional vascular area in patients with VE and/or RV.

    Conclusions:

    • Colonic vascular ectasias are a complication of portal hypertension in alcoholic cirrhotic patients.
    • Colonic VE and RV are endoscopic features of portal hypertensive colopathy, with colonic mucosal capillary ectasia as the pathological basis.
    • These findings highlight a spectrum of vascular abnormalities in the gastrointestinal tract related to portal hypertension.