Related Experiment Video

Updated: Jul 15, 2026

A High-content Assay for Monitoring AMPA Receptor Trafficking
10:34

A High-content Assay for Monitoring AMPA Receptor Trafficking

Published on: January 28, 2019

Diffusional trapping of GluR1 AMPA receptors by input-specific synaptic activity

Michael D Ehlers1, Martin Heine, Laurent Groc

  • 1Department of Neurobiology, Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710, USA. ehlers@neuro.duke.edu

Neuron
|May 8, 2007
PubMed
Summary

Synaptic activity immobilizes GluR1 AMPA receptors at synapses. This local restriction of receptor mobility drives synapse-specific accumulation, enhancing synaptic strength.

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