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Two Methods for Establishing Primary Human Endometrial Stromal Cells from Hysterectomy Specimens
Published on: May 23, 2014
Polarized expression of major histocompatibility complex class I molecules in human endometrial and endocervical
M A Van Eijkeren1, P J Peters, H J Geuze
1Department of Obstetrics and Gynaecology, University Hospital, Utrecht, The Netherlands.
Abstract:
The localization of major histocompatibility complex (MHC) class I molecules in human endometrial and endocervical epithelial cells was studied with an immunogold technique on ultrathin cryosections. At the cell surface, MHC class I molecules are delivered solely to the basolateral plasma membrane in human epithelia. Therefore, only the basolateral domain of epithelial cells is capable of presenting antigen to MHC class I-restricted cytotoxic T cells.
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