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Published on: October 18, 2024
Effectiveness of intrauterine insemination in subfertile couples with an isolated cervical factor: a randomized
Pieternel Steures1, Jan Willem van der Steeg, Peter G A Hompes
1Department of Obstetrics and Gynecology, Vrije Universiteit Medical Center, Amsterdam, the Netherlands. pn.steures@amc.uva.nl
Abstract:
After randomization of subfertile couples with an isolated cervical factor to intrauterine insemination for 6 months or expectant management for 6 months, 26 women (51%) vs. 16 women (33%) conceived, respectively. Of these pregnancies, 22 (43%) vs. 13 (27%) were ongoing (relative risk, 1.6; 95% confidence interval, 0.91 to 2.8). There was one multiple pregnancy in the group that was allocated to intrauterine insemination. This trial suggests a beneficial effect of IUI in couples with an isolated cervical factor.
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