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Published on: December 11, 2017
Influence of socioeconomic status on survival after primary aortic or mitral valve replacement
J P Bagger1, M-B Edwards, K M Taylor
1United Kingdom Heart Valve Registry, Cardiothoracic Directorate, Hammersmith Hospital, London, UK. p.bagger@ic.ac.uk
Insights
Socioeconomic status impacts long-term survival after aortic or mitral valve replacement. Patients from less deprived areas experienced better long-term outcomes, particularly women.
Area of Science:
- Cardiovascular Surgery
- Public Health
- Health Outcomes Research
Background:
- Socioeconomic status (SES) is a known determinant of health, but its specific impact on outcomes following major cardiac surgery like valve replacement requires detailed investigation.
- Understanding these disparities is crucial for developing targeted interventions and improving equitable healthcare delivery.
Purpose of the Study:
- To investigate the association between socioeconomic status and patient outcomes after first-time aortic or mitral valve replacement.
- To determine if social deprivation influences short-term and long-term survival rates in this patient population.
Main Methods:
- Analysis of data from the United Kingdom (UK) Heart Valve Registry, including 51,844 patients undergoing primary aortic or mitral valve replacement between 1986 and 2001.
- Stratification of patients based on the Carstairs deprivation score, derived from 1991 UK Census data linked to patient postcodes.
- Evaluation of 30-day, 1-year, and long-term (up to 15 years) survival rates across different socioeconomic levels.
Main Results:
- Short-term (30-day and 1-year) survival rates were comparable across all socioeconomic groups.
- Long-term survival was significantly higher in the least deprived socioeconomic group compared to the most deprived groups.
- Women in the most deprived socioeconomic levels had an 18% lower survival rate than those in the least deprived level; men showed a 7% lower survival rate.
Conclusions:
- Disadvantaged socioeconomic background negatively affects long-term survival following aortic or mitral valve replacement.
- The disparity in long-term outcomes is particularly pronounced among women, highlighting gender-specific vulnerabilities related to social deprivation.
- Factors associated with long-term mortality included biological valves, mitral valve position, female gender, and lower socioeconomic status.
Objectives:
We sought to evaluate whether socioeconomic status influences outcome after first-time single aortic or mitral valve replacement.
Setting:
National Heart Valve registry.
Design And Patients:
Between 1 January 1986 and 31 December 2001, 51 844 consecutive patients who underwent primary aortic or mitral valve replacement were registered on the United Kingdom (UK) Heart Valve Registry. Data included age, gender, valve position, type of valve implant, postcode, follow-up time, date and cause of death. The Carstairs deprivation score (1991 Census data for the UK) was used to stratify cases by level of social deprivation according to postcodes.
Results:
Both 30-day and 1-year survival/mortality rates were similar across all socioeconomic levels. However, long-term survival rate (up to 15 years) was significantly higher in the least deprived socioeconomic level than in the two most deprived levels. There was an 18% lower survival rate amongst women in the most deprived levels (35.9%, 95% CI: 32.4 to 39.4) versus the least deprived level (43.7%, 95% CI: 38.1 to 49.2, p<0.004). In men, survival in the most deprived levels (39.5%, 95% CI: 36.4 to 42.5) was 7% lower than in the least deprived level (42.7%, 95% CI: 37.7 to 47.7, p<0.005). Biological valve, mitral position, female gender, and low socioeconomic status were all associated with long-term mortality.
Conclusions:
A disadvantaged social background has a negative influence on long-term survival after aortic or mitral valve replacement, especially among women.
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