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Updated: Jul 15, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Preparation of porous hydroxyapatite with interconnected pore architecture
1Multiphase Reaction Laboratory, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, PR China.
Abstract:
Since pore connectivity has significant effects on the biological behaviors of biomedical porous hydroxyapatite (PHA), the preparation of PHA with interconnected pore architecture is of great practical significance. In the present study, PHA with highly interconnected architecture was prepared via a simple burnout route with rod-like urea as the porogen. Microscopy and porosimetry data showed that the as-prepared PHA had open and interconnected pore structure with the average fenestration size of about 120 microm. Open pores occupied up to 98% of the total porosity. The compressive strength and modulus of the as-prepared PHA were respectively 1.3-7.6 MPa and 4.0-10.4 GPa.
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