Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Finite Element Simulation of Opening Angle Response of Porcine Aortas Using Layer Specific GAG Distributions in One and Two Layered Solid Matrices.

Cardiovascular engineering and technology·2024
Same author

Glycosaminoglycans modulate compressive stiffness and circumferential residual stress in the porcine thoracic aorta.

Acta biomaterialia·2023
Same author

Intramural Distributions of GAGs and Collagen vs. Opening Angle of the Intact Porcine Aortic Wall.

Annals of biomedical engineering·2022
Same author

The Contribution of Glycosaminoglycans/Proteoglycans to Aortic Mechanics in Health and Disease: A Critical Review.

IEEE transactions on bio-medical engineering·2021
Same author

Intramural Glycosaminoglycans Distribution vs. Residual Stress in Porcine Ascending Aorta: a Computational Study<sup>.</sup>

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2020
Same author

Significant Fatigue Life Enhancement in Multiscale Doubly-Modified Fiber/Epoxy Nanocomposites with Graphene Nanoplatelets and Reduced-Graphene Oxide.

Polymers·2020

Related Experiment Video

Updated: Jul 15, 2026

An Ex Vivo Porcine Model for Hydrodynamic Testing of Experimental Aortic Valve Procedures and Novel Medical Devices
06:56

An Ex Vivo Porcine Model for Hydrodynamic Testing of Experimental Aortic Valve Procedures and Novel Medical Devices

Published on: August 25, 2023

Aortic valve leaflet sizer: a new device for aortic valve sparing.

Michel R Labrosse1, Carsten J Beller

  • 1University of Ottawa, Department of Mechanical Engineering, Ottawa, Ontario, Canada. labrosse@eng.uottawa.ca

The Journal of Heart Valve Disease
|May 9, 2007
PubMed
Summary

A new sizer tool accurately measures aortic valve leaflet dimensions during valve-sparing surgery. This device aids surgeons in achieving better patient outcomes by ensuring valve competence.

More Related Videos

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Related Experiment Videos

Last Updated: Jul 15, 2026

An Ex Vivo Porcine Model for Hydrodynamic Testing of Experimental Aortic Valve Procedures and Novel Medical Devices
06:56

An Ex Vivo Porcine Model for Hydrodynamic Testing of Experimental Aortic Valve Procedures and Novel Medical Devices

Published on: August 25, 2023

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering
  • Anatomical Measurement

Background:

  • Aortic valve-sparing surgery aims to preserve the native valve, but requires precise dimension correction for full competence.
  • Accurate measurement of leaflet height and free edge length is crucial for successful aortic valve repair.

Purpose of the Study:

  • To design and evaluate a novel sizer for simultaneously measuring aortic leaflet height and free edge length.
  • To assess the usability and dependability of the sizer in guiding aortic valve-sparing procedures.

Main Methods:

  • Development of a prototype sizer specifically for aortic valve leaflet dimensions.
  • Testing the sizer prototype in porcine hearts of varying sizes to validate measurements.

Main Results:

  • The sizer prototype was successfully built and utilized in porcine heart models.
  • The sizer demonstrated ease of use and provided dependable measurements of aortic leaflet dimensions.

Conclusions:

  • The developed sizer is a valuable new resource for surgeons performing aortic valve-sparing surgery.
  • Accurate intraoperative measurement using this sizer can lead to improved outcomes in aortic valve repair.