Related Experiment Video
Updated: Jul 15, 2026
Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
Surgical outcome in tuberous sclerosis complex: a multicenter survey
Deepak Madhavan1, Sarah Schaffer, Alexei Yankovsky
1Comprehensive Epilepsy Center, Department of Neurology, NYU Medical Center, 403 East 34th Street, New York, NY 10016, U.S.A. madhad01@med.nyu.edu
Abstract:
Multicenter, retrospective analysis of 70 subjects with TSC following surgery for relief of epilepsy revealed significant associations between younger age at seizure onset, present/prior history of infantile spasms, interictal focality (bilateral versus unilateral), and absence of residual postoperative predominant tuber, and poorer postoperative outcome (p < 0.01). Ictal multifocality, mental retardation, and discordant EEG and MRI data showed a negative trend toward outcome, but were not significant.
