Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Testes: Histology01:27

Testes: Histology

A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...
Spermatogenesis01:22

Spermatogenesis

Spermatogenesis is a complex process that involves the development of sperm cells from undifferentiated stem cells in the seminiferous tubules of the testes. The process is essential for the production of mature and functional sperm cells that are capable of fertilizing an egg.
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...
Testes: Gross Anatomy01:19

Testes: Gross Anatomy

The testes, also known as testicles, are the male gonads. They are housed within the scrotum, a sac-like structure located beneath the penis. The scrotum's primary role is to regulate the temperature of the testes, which is crucial for sperm production.
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pyeloplasty with ureteral stent placement in children: Do prophylactic antibiotics serve a purpose?

Journal of pediatric urology·2022
Same author

Optimal Timing of Surgical Procedures in Pediatric Patients.

Journal of neurosurgical anesthesiology·2016
Same author

Innovation in Robotics and Pediatric Urology: Robotic Ureteroureterostomy for Duplex Systems with Ureteral Ectopia.

Journal of endourology·2016
Same author

Intra- and inter-observer variability of functional MR urography (fMRU) assessment in children.

Pediatric radiology·2016
Same author

Transitional care in pediatric urology.

Seminars in pediatric surgery·2015
Same author

Serum cystatin C as a novel marker to differentiate pseudoazotemia in the setting of intraperitoneal urine extravasation.

Urology·2015

Related Experiment Video

Updated: Jul 15, 2026

Teratoma Generation in the Testis Capsule
05:24

Teratoma Generation in the Testis Capsule

Published on: November 7, 2011

Infertility and testis cancer.

Sarah M Lambert1, Harry Fisch

  • 1Male Reproductive Center, Department of Urology, Columbia University, College of Physicians and Surgeons, New York Presbyterian Hospital, 944 Park Avenue, New York, NY 10028, USA.

The Urologic Clinics of North America
|May 9, 2007
PubMed
Summary

Testicular cancer impacts young men's fertility. Understanding cancer and treatment effects is crucial for preserving reproductive health in germ cell neoplasm patients.

Area of Science:

  • Oncology
  • Reproductive Medicine
  • Urology

Background:

  • Testicular cancer is the most common solid organ tumor in young men, affecting their reproductive years.
  • Current treatments improve survival but often lead to adverse fertility outcomes.
  • Germ cell neoplasms require a comprehensive understanding of their impact on male fertility.

Purpose of the Study:

  • To elucidate the multifaceted effects of testicular cancer and its treatments on male fertility.
  • To identify key factors influencing fertility preservation in men with germ cell neoplasms.
  • To provide insights for restoring and maintaining fertility in affected individuals.

Main Methods:

  • Review of existing literature on testicular cancer, neoplasia effects, and treatment modalities.

More Related Videos

Germ Cell Transplantation and Testis Tissue Xenografting in Mice
10:41

Germ Cell Transplantation and Testis Tissue Xenografting in Mice

Published on: February 6, 2012

Related Experiment Videos

Last Updated: Jul 15, 2026

Teratoma Generation in the Testis Capsule
05:24

Teratoma Generation in the Testis Capsule

Published on: November 7, 2011

Germ Cell Transplantation and Testis Tissue Xenografting in Mice
10:41

Germ Cell Transplantation and Testis Tissue Xenografting in Mice

Published on: February 6, 2012

  • Analysis of the impact of chemotherapy, radiotherapy, and retroperitoneal lymph node dissection on reproductive function.
  • Synthesis of information regarding fertility outcomes and preservation strategies.

    • Main Results:

    • Testicular cancer and systemic effects of neoplasia significantly compromise male fertility.
    • Therapeutic interventions including chemotherapy, radiotherapy, and surgery can lead to irreversible fertility loss.
    • Understanding these impacts is essential for developing effective fertility preservation strategies.

    Conclusions:

    • Restoring and maintaining fertility in men with germ cell neoplasms requires a thorough understanding of cancer and treatment-related effects.
    • Proactive fertility management should be integrated into the care of young men diagnosed with testicular cancer.
    • Further research is needed to optimize fertility preservation and restoration techniques.