Related Experiment Video
Updated: Jul 15, 2026

05:46
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Thumb subungual melanoma: is amputation necessary?
Sukh S Rayatt1, Anne L Dancey, Paul M Davison
1Department of Plastic and Reconstructive Surgery, University Hospital of North Staffordshire, Stoke City Hospital, Stoke-on-Trent, UK. sukhrayatt@yahoo.co.uk
Summary
A new conservative approach for subungual melanoma of the thumb preserves digit length and function. This digit-sparing technique, involving local excision and flap reconstruction, shows promising results with minimal disability.
Area of Science:
- Oncology
- Dermatology
- Surgical Oncology
Background:
- Subungual melanoma is a rare cancer.
- Traditional treatment involves digit amputation.
- Thumb involvement leads to significant functional and aesthetic deficits.
Purpose of the Study:
- To present a novel, conservative, digit-sparing surgical approach for subungual melanoma of the thumb.
- To evaluate the efficacy and outcomes of this approach.
Main Methods:
- Four patients with subungual melanoma of the thumb underwent local excision with 1cm margins.
- Excision extended to the periosteum.
- Reconstruction was performed using local flaps.
Main Results:
- Minimum follow-up of 6 years.
- One recurrence was observed.
- No deaths occurred in the study cohort.
- The conservative approach preserved digit length and minimized disability.
Conclusions:
- Selected cases of subungual melanoma of the thumb can be managed conservatively.
- Digit-sparing surgery allows for preservation of function and aesthetics.
- This approach offers a viable alternative to amputation.
Related Concept Videos
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Diabetic Foot Ulcer
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...
Accessory Structures of the Skin: Nails
Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
