Related Experiment Video
Updated: Jul 15, 2026

06:47
Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
Egg yolk soluble protein stimulates the proliferation and differentiation of osteoblastic MC3T3-E1 cells
MinYoung Ji1, Kang-Hyun Leem, Mujo Kim
1Pharma Foods International Co, Kyoto, Japan.
Bioscience, Biotechnology, and Biochemistry
|May 9, 2007
Abstract:
We determined the effects of yolk water-soluble protein (YSP) on bone formation in pre-osteoblastic MC3T3-E1 cells. YSP (50-5,000 microg/ml) increased cell proliferation and collagen content. Alkaline phosphatase (ALP) activity was also increased by YSP treatment. After enhancement of ALP activity, significant augmentation of calcification was observed. These results suggest that YSP is a promising agent for the prevention and treatment of bone loss.

