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NMR-guided fragment-based approach for the design of tRNA(Lys3) ligands

Florence Chung1, Carine Tisné, Thomas Lecourt

  • 1Chimie Thérapeutique, Université Paris Descartes, CNRS, 4 avenue de l'Observatoire, 75006 Paris, France.

Angewandte Chemie (International Ed. in English)
|May 9, 2007
PubMed
Abstract

No abstract available in PubMed .

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Conserved Binding Sites01:49

Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
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