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Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Computed Tomography01:10

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Related Experiment Video

Updated: Dec 31, 2025

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
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Method for identifying calcified plaque in contrast enhanced computed tomography.

Melissa Daly1, J Jeffrey Carr, Joel D Stitzel

  • 1Wake Forest University School of Medicine, USA.

Biomedical Sciences Instrumentation
|May 10, 2007
PubMed
Summary

A new computed tomography technique allows for arteriosclerosis diagnosis using a single contrast-enhanced scan. This method accurately measures calcified plaque volume, reducing costs and improving patient care.

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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
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Area of Science:

  • Medical Imaging
  • Cardiovascular Disease
  • Radiology

Background:

  • Arteriosclerosis contributes to significant mortality and healthcare expenses.
  • Diagnosis relies on aortic wall thickness and calcified plaque volume, typically requiring separate computed tomography (CT) scans.
  • Contrast-enhanced CT is used for wall thickness, while un-enhanced CT is used for plaque volume.

Purpose of the Study:

  • To introduce a novel CT technique for assessing arteriosclerosis.
  • To enable simultaneous measurement of aortic wall thickness and calcified plaque volume from a single contrast-enhanced scan.
  • To improve diagnostic efficiency and reduce healthcare costs associated with arteriosclerosis assessment.

Main Methods:

  • A new technique for measuring calcified plaque volume from contrast-enhanced CT scans was developed.
  • The method adjusts for variations in contrast intensity on a slice-by-slice basis.
  • This adjustment accounts for similar intensity values between contrast and calcified plaque.

Main Results:

  • The technique demonstrated the ability to measure calcified plaque volume using contrast-enhanced scans.
  • Results from the novel technique were compared to those obtained from traditional un-enhanced scans.
  • Calculated calcified plaque volumes showed high correlation with un-enhanced scan results (slope=1.0611, r-squared = 0.9974).

Conclusions:

  • The proposed CT technique accurately quantifies calcified plaque volume from contrast-enhanced scans.
  • This single-scan approach simplifies arteriosclerosis diagnosis.
  • The method offers a more robust and efficient alternative for assessing key diagnostic markers of arteriosclerosis.