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Published on: January 13, 2016
Pathogen profiling for disease management and surveillance
Vitali Sintchenko1, Jonathan R Iredell, Gwendolyn L Gilbert
1Centre for Infectious Diseases and Microbiology Public Health, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Western Clinical School, The University of Sydney, New South Wales, Australia. vitalis@icpmr.wsahs.nsw.gov.au
Abstract:
The usefulness of rapid pathogen genotyping is widely recognized, but its effective interpretation and application requires integration into clinical and public health decision-making. How can pathogen genotyping data best be translated to inform disease management and surveillance? Pathogen profiling integrates microbial genomics data into communicable disease control by consolidating phenotypic identity-based methods with DNA microarrays, proteomics, metabolomics and sequence-based typing. Sharing data on pathogen profiles should facilitate our understanding of transmission patterns and the dynamics of epidemics.
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