Nursing perspectives on intraperitoneal chemotherapy

During the past decade, a number of studies have established that there is a considerable pharmacologic advantage to direct intraperitoneal instillation of chemotherapy for treatment of cancer confined to the abdominal cavity. This article explores the history, present status, and future directions of intraperitoneal chemotherapy. The therapeutic advantages, various chemotherapeutic agents used, delivery systems, administration procedures, toxic effects, and nursing management are addressed.