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Probiotics in paediatric gastrointestinal diseases
Daniel A Lemberg1, Chee Yee Ooi, Andrew S Day
1School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia.
Probiotics are generally safe but scientific evidence for many benefits is limited. This review focuses on proven uses in children, specifically for acute diarrhoea and antibiotic-associated diarrhoea.
Area of Science:
- Gastroenterology
- Microbiology
Background:
- Probiotics are increasingly popular for purported health benefits.
- Scientific evidence supporting many claimed probiotic uses is often insufficient.
- Probiotics are generally well-tolerated and safe.
Purpose of the Study:
- To review the scientific evidence for probiotics in various gastrointestinal disorders.
- To specifically evaluate the role of probiotics in managing acute diarrhoea and antibiotic-associated diarrhoea in children.
Main Methods:
- Literature review of studies on probiotic efficacy.
- Focus on pediatric gastrointestinal conditions.
Main Results:
- Probiotics have well-established roles in treating acute diarrhoeal illness in children.
- Probiotics are also effective for antibiotic-associated diarrhoea in pediatric populations.
- Evidence for other gastrointestinal disorders remains less robust.
Conclusions:
- Probiotics are beneficial for specific pediatric gastrointestinal issues like acute and antibiotic-associated diarrhoea.
- Further research is needed to substantiate claims for other uses.
- The safety profile of probiotics is favorable.
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