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Arthritis suppression by NADPH activation operates through an interferon-beta pathway

Peter Olofsson1, Annika Nerstedt, Malin Hultqvist

  • 1Biovitrum AB, Arvid Wallgrens Backe 20, Göteborg, Sweden. peter.olofsson@biovitrum.com

BMC Biology
|May 11, 2007
PubMed
Summary

Genetic variations in NCF1 influence arthritis severity. Activating NADPH oxidase with phytol protects against arthritis by modulating interferon pathways, similar to protective NCF1 genetic variants.

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