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Related Concept Videos

Cranial Bones: Lateral View01:27

Cranial Bones: Lateral View

The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Sutures of the Skull01:22

Sutures of the Skull

The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

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Updated: Jul 15, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Chondrosarcoma of the temporal bone.

Mizuho Yagisawa1, Junichi Ishitoya, Mamoru Tsukuda

  • 1Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. DZF14260@hyo-med.ac.jp

Auris, Nasus, Larynx
|May 11, 2007
PubMed
Summary

A rare myxoid chondrosarcoma of the temporal bone caused progressive hearing loss in a 52-year-old woman. Surgical removal resulted in no recurrence 45 months post-operation.

Area of Science:

  • Oncology
  • Otolaryngology
  • Pathology

Background:

  • Chondrosarcoma of the temporal bone is an exceptionally rare malignancy.
  • Fewer than 40 cases have been documented in English literature, highlighting its rarity.

Observation:

  • A 52-year-old female presented with progressive hearing loss as the sole symptom.
  • Imaging and subsequent histological examination confirmed a myxoid chondrosarcoma of the temporal bone.

Findings:

  • The tumor was successfully excised using aspiration, mastoidectomy, and tympanotomy.
  • The surgical procedure preserved the jugular bulb.
  • No evidence of tumor recurrence was observed at the 45-month follow-up.

Implications:

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Surgical Treatment of an Endolymphatic Sac Tumor
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Endoscopic Cholesteatoma Surgery
08:47

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Published on: January 19, 2022

  • This case contributes to the limited understanding of temporal bone chondrosarcomas.
  • It demonstrates a potentially effective surgical management strategy for this rare tumor.
  • Early diagnosis and complete surgical resection appear crucial for favorable outcomes.