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Updated: Jul 15, 2026
Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Management of the exposure of e-PTFE membranes in guided bone regeneration
Simone Verardi1, Massimo Simion
1Department of Periodontics, University of Washington, Seattle, WA 98195-7444, USA. sverardi@u.washington.edu
Unlabelled:
Guided bone regeneration (GBR) has been used extensively since its introduction in the late 1980s. In such treatment, e-PTFE membranes are often preferred because of their inert biological features and the predictability of the barrier effect. One complication of GBR is the premature exposure of the membrane. A consequence of the resulting soft tissue dehiscence is compromised bone regeneration. There are situations in which an exposed membrane can be maintained and obtain satisfactory results. This article discusses suggested guidelines for the treatment of exposed e-PTFE membranes.
Learning Objectives:
This article discusses treatment options for e-PTFE membranes that are exposed with or without infection. Upon reading this article, the reader should: Be able to identify both Class I and Class II exposures. Understand how to properly treat both a Class I and Class II exposed e-PTFE membrane.
