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Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

Puck Knipscheer1, Willem J van Dijk, Jesper V Olsen

  • 1Department of Molecular Carcinogenesis, The Netherlands Cancer Institute and Center for Biomedical Genetics, Plesmanlaan, Amsterdam, The Netherlands.

The EMBO Journal
|May 12, 2007
PubMed
Summary

Small Ubiquitin-like Modifier (SUMO) chain formation is promoted by noncovalent interactions between Ubc9 and SUMO. This interaction is key for poly-sumoylation, similar to ubiquitin chain assembly.

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