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Updated: Jul 15, 2026

Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
Published on: June 5, 2019
[Ventilation-perfusion distributions in the lungs. A novel technique for rapid measurement]
B Dünges1, J Karmrodt, J E Baumgardner
1Klinik für Anästhesiologie, Johannes-Gutenberg-Universität, Langenbeckstr. 1, 55131 Mainz. duenges@anaesthesie.klinik.uni-mainz.de
Abstract:
The multiple inert gas elimination technique (MIGET) represents the gold standard for analysis of ventilation and perfusion distributions in the lung. Modification of this technique allows a much simpler sample processing and hence permits routine clinical application of this technique. MIGET using micropore membrane inlet mass spectrometry (MMIMS) might, therefore, facilitate early diagnosis of lung diseases and monitoring of therapeutic interventions in the future.
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