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Updated: Jul 15, 2026

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Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
Published on: July 1, 2018
[Meningitis caused by Streptococcus suis]
S Braun1, G Jechart, U Emmerling
1Institut für Laboratoriumsmedizin, Mikrobiologie und Umwelthygiene, Klinikum Augsburg.
Deutsche Medizinische Wochenschrift (1946)
|May 12, 2007
Summary
A butcher developed Streptococcus suis (S. suis) meningitis after occupational exposure. Early diagnosis and treatment are crucial to prevent complications like hearing loss.
Area of Science:
- Infectious Diseases
- Bacteriology
- Neurology
Background:
- Streptococcus suis (S. suis) is an emerging zoonotic pathogen.
- Occupational exposure, particularly in swine handlers, poses a risk for S. suis infection.
- Bacterial meningitis remains a significant cause of morbidity and mortality.
Observation:
- A butcher presented with symptoms of meningitis, including headache, fever, and nuchal rigidity.
- The patient had a history of frequent hand and forearm cuts, suggesting a potential exposure route.
- Cerebrospinal fluid analysis revealed elevated leukocytes and Gram-positive bacteria.
Findings:
- Blood and cerebrospinal fluid cultures confirmed Streptococcus suis (S. suis) infection.
- The patient was treated with ampicillin and ceftriaxone.
- Sequelae included hearing impairment and vestibular dysfunction, indicating vestibulocochlear nerve involvement.
Implications:
- This case highlights the importance of considering S. suis in meningitis cases with occupational exposure to pigs.
- Prompt diagnosis and appropriate antibiotic therapy are essential for favorable outcomes.
- Neurological and audiological sequelae underscore the severity of S. suis infections.
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