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Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
07:26

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model

Published on: July 1, 2018

[Meningitis caused by Streptococcus suis]

S Braun1, G Jechart, U Emmerling

  • 1Institut für Laboratoriumsmedizin, Mikrobiologie und Umwelthygiene, Klinikum Augsburg.

Deutsche Medizinische Wochenschrift (1946)
|May 12, 2007
PubMed
Abstract

Insights

A butcher developed Streptococcus suis (S. suis) meningitis after occupational exposure. Early diagnosis and treatment are crucial to prevent complications like hearing loss.

Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Neurology

Background:

  • Streptococcus suis (S. suis) is an emerging zoonotic pathogen.
  • Occupational exposure, particularly in swine handlers, poses a risk for S. suis infection.
  • Bacterial meningitis remains a significant cause of morbidity and mortality.

Observation:

  • A butcher presented with symptoms of meningitis, including headache, fever, and nuchal rigidity.
  • The patient had a history of frequent hand and forearm cuts, suggesting a potential exposure route.
  • Cerebrospinal fluid analysis revealed elevated leukocytes and Gram-positive bacteria.

Findings:

  • Blood and cerebrospinal fluid cultures confirmed Streptococcus suis (S. suis) infection.
  • The patient was treated with ampicillin and ceftriaxone.
  • Sequelae included hearing impairment and vestibular dysfunction, indicating vestibulocochlear nerve involvement.

Implications:

  • This case highlights the importance of considering S. suis in meningitis cases with occupational exposure to pigs.
  • Prompt diagnosis and appropriate antibiotic therapy are essential for favorable outcomes.
  • Neurological and audiological sequelae underscore the severity of S. suis infections.

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