Related Experiment Video
Updated: Jul 15, 2026

10:38
DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
Published on: February 1, 2020
Solid pancreatic hamartoma
Shigenori Nagata1, Koji Yamaguchi, Takahiro Inoue
1Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. shnagata@surgpath.med.kyushu-u.ac.jp
Pathology International
|May 12, 2007
Summary
A rare solid pancreatic hamartoma was found incidentally in a patient. This non-cancerous pancreatic mass was successfully resected, with no recurrence observed post-surgery.
Area of Science:
- Gastroenterology and Hepatology
- Surgical Pathology
- Oncology
Background:
- Solid pancreatic hamartoma is an extremely rare, non-neoplastic pancreatic lesion.
- Distinguishing it from pancreatic endocrine tumors preoperatively can be challenging.
Observation:
- A 58-year-old woman presented with an incidentally discovered pancreatic nodule.
- Imaging revealed a 2.0 cm pancreatic body mass with delayed enhancement on CT.
- Histopathology confirmed a solid hamartoma composed of disorganized pancreatic tissue and CD34/CD117-positive spindle cells.
Findings:
- The case represents one of the few documented instances of solid pancreatic hamartoma.
- The lesion was successfully treated with distal pancreatectomy.
- No recurrence was noted five months post-operation.
Implications:
- This case contributes to the limited literature on solid pancreatic hamartomas.
- Accurate preoperative diagnosis and surgical management are crucial for rare pancreatic lesions.
- Further research may clarify the pathogenesis and optimal management of pancreatic hamartomas.

