Related Experiment Videos
Long-term results of Ahmed glaucoma valve implantation for uveitic glaucoma
Thekla G Papadaki1, Ioannis P Zacharopoulos, Louis R Pasquale
1Massachusetts Eye Research and Surgery Institute, Ocular Immunology and Uveitis Foundation, Harvard Medical School Boston, Massachusetts, USA. theklapap@med.uoc.gr
Insights
Ahmed glaucoma valve implantation offers moderate success for uveitic glaucoma, with long-term outcomes improved by medication. Corneal complications are the most frequent serious issue.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Uveitis Management
Background:
- Uveitic glaucoma presents unique challenges in intraocular pressure (IOP) management.
- Ahmed glaucoma valve implantation is a surgical option for refractory cases.
Purpose of the Study:
- To evaluate the long-term efficacy and safety of Ahmed glaucoma valve implantation in patients with uveitic glaucoma.
Main Methods:
- Retrospective chart review of 60 patients with uveitic glaucoma undergoing Ahmed valve implantation.
- Success defined by IOP targets (5-21 mm Hg, 25% reduction) and absence of serious complications.
- Follow-up averaged 30 months, with specific analysis at one and four years.
Main Results:
- One-year success rates were 77% (IOP control) and 57% (qualified success).
- Four-year success rates decreased to 50% (IOP control) and 39% (qualified success).
- Corneal complications were the most common serious adverse events, particularly in patients with pre-existing corneal disease.
Conclusions:
- Ahmed valve implantation is a safe and moderately effective procedure for uveitic glaucoma.
- Sustained IOP control often requires adjunctive glaucoma medications.
- Careful patient selection is advised due to the risk of corneal complications.
Purpose:
To present long-term outcomes of Ahmed glaucoma valve implantation for uveitic glaucoma.
Design:
Interventional case series.
Methods:
Retrospective chart review of 60 patients (60 eyes) with uveitic glaucoma who underwent Ahmed valve implantation over a four-year period at a tertiary uveitis referral center. Success definition 1 included patients with an intraocular pressure (IOP) between 5 and 21 mm Hg, reduced by 25% from that before implantation. Success definition 2 (qualified success) excluded those patients in whom serious complications occurred.
Results:
Mean follow-up time was 30 months (range, six to 87 months; four-year results relate to a cohort of 15 patients). Success rates were 77% and 50% and qualified success rates were 57% and 39% at one and four years, respectively. At four years, 74% of the patients required glaucoma medication to maintain IOP control. The overall complication rate was 12%/person-years. The rate of visual acuity loss was 4%/person-years; that was most commonly attributed to corneal complications that were more likely to occur in patients with preoperative corneal disease (P = .01, Fisher exact test).
Conclusions:
Ahmed glaucoma valve implantation is a safe yet moderately successful procedure for uveitic glaucoma. Long-term success rates are enhanced with the use of glaucoma medications, and corneal complications are the most common of all potential serious complications.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview