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Candida inferior vena cava filter infection and septic thrombophlebitis

M S Meda1, A J Lopez, A Guyot

  • 1Department of Microbiology, Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, UK.

The British Journal of Radiology
|May 15, 2007
PubMed

Insights

Candida glabrata can infect central venous catheters, leading to rare septic thrombophlebitis. This case highlights C. glabrata infecting an inferior vena cava filter after femoral vein septic thrombophlebitis.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Central venous catheterization (CVC) is associated with Candida infections, commonly Candida albicans.
  • Candida glabrata is a less frequent cause of CVC-related infections.
  • Septic thrombophlebitis of central veins is an uncommon CVC complication.

Observation:

  • This report details the first known case of inferior vena cava (IVC) filter infection by Candida glabrata.
  • The infection occurred subsequent to septic thrombophlebitis of the femoral veins.
  • The patient had undergone central venous catheterization.

Findings:

  • Candida glabrata successfully infected an IVC filter in the context of deep vein thrombosis.
  • This represents a novel presentation of a rare fungal complication following CVC placement.
  • The case underscores the potential for C. glabrata to cause severe vascular complications.

Implications:

  • Highlights the need for vigilance regarding C. glabrata in CVC-related bloodstream infections, especially with thrombotic complications.
  • Suggests that IVC filters may be a potential nidus for fungal biofilm formation and infection.
  • Informs management strategies for rare fungal septic thrombophlebitis involving central venous hardware.

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