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Reversible decrease of fluoride resistant acid phosphatase-positive neurons after herpes simplex virus infection
R B Tenser1, A L Viselli, D H Savage
1Department of Medicine, Penn State University College of Medicine, Hershey 17033.
Neuroscience Letters
|September 2, 1991
Abstract:
Herpes simplex virus (HSV) frequently infects human sensory ganglion neurons, and similar infections have been reported in experimental animals. Reported here is an investigation of in vivo neuronal function after HSV infection. It was observed that the proportion of fluoride resistant acid phosphatase (FRAP)-positive trigeminal ganglion neurons was decreased for several months after experimental infection of mice, and it is suggested that other neuronal functions may also be altered by HSV.