Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

iPS Cell Differentiation

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The lipedema common case report form as a research tool: standardizing lipedema data collection.

Frontiers in global women's health·2026

Same author

Evolving Landscape of Glioblastoma Research: Integrating Therapeutic Advances and Diagnostic Frontiers.

Brain sciences·2026

Same author

Microbe-associated molecular patterns differentially mediate carcinogenic alterations of the breast tissue in the context of obesity.

Neoplasia (New York, N.Y.)·2026

Same author

Editorial: Role of induced pluripotent stem cells (iPSCs) in regenerative medicine, disease modeling and drug discovery.

Frontiers in bioengineering and biotechnology·2025

Same author

Oncogenic effects of ECM remodeling in obesity and breast cancer.

Oncogene·2025

Same author

Adipose Stromal Cell Heterogeneity and Trafficking: Implications for Breast Cancer Metastasis and Obesity.

Frontiers in bioscience (Landmark edition)·2025

Search research articles

Related Experiment Video

Updated: Jul 15, 2026

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues

Published on: March 31, 2016

Adipose-derived stem cells for regenerative medicine.

Jeffrey M Gimble¹, Adam J Katz, Bruce A Bunnell

¹Stem Cell Biology Laboratory and Clinical Nutrition Research Unit, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA. gimblejm@pbrc.edu

Circulation Research

|May 15, 2007

Summary

Adipose-derived stem cells (ASCs) are a promising source for regenerative medicine. This review covers their isolation, characteristics, and applications in preclinical and clinical settings.

More Related Videos

Efficient Isolation of Adipose-derived Stem Cells and Adipocytes from Porcine Adipose Tissue

Efficient Isolation of Adipose-derived Stem Cells and Adipocytes from Porcine Adipose Tissue

Published on: May 26, 2026

Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells

Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells

Published on: March 5, 2019

Related Experiment Videos

Last Updated: Jul 15, 2026

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues

Published on: March 31, 2016

Efficient Isolation of Adipose-derived Stem Cells and Adipocytes from Porcine Adipose Tissue

Efficient Isolation of Adipose-derived Stem Cells and Adipocytes from Porcine Adipose Tissue

Published on: May 26, 2026

Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells

Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells

Published on: March 5, 2019

Area of Science:

Regenerative Medicine
Stem Cell Biology
Tissue Engineering

Background:

Regenerative medicine needs reliable stem cell sources.
Adipose tissue is abundant and accessible.
Adult stem cells can differentiate into multiple cell types.

Purpose of the Study:

Review the isolation and characterization of adipose-derived stem cells (ASCs).
Discuss the preclinical and clinical applications of ASCs.
Highlight ASCs as a key component for regenerative medicine.

Main Methods:

Literature review of studies on ASCs.
Analysis of isolation and characterization techniques.
Evaluation of preclinical and clinical trial data.

Main Results:

ASCs can be reliably isolated from adipose tissue.
ASCs exhibit multipotent differentiation capabilities.
ASCs show potential in various therapeutic applications.

Conclusions:

Adipose-derived stem cells are a viable and abundant stem cell source.
ASCs are crucial for advancing regenerative medicine therapies.
Further research and clinical translation of ASCs are warranted.