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Melioidosis presenting as genitourinary infection in two men with diabetes
B S Viswaroop1, V Balaji, E Mathai
1Department of Urology, Christian Medical College, Vellore, India.
Abstract:
Melioidosis is an infectious disease caused by Burkholderia pseudomallei. It occurs predominantly in tropical regions. The manifestations are protean which include pneumonia, visceral abscesses, septic arthritis, osteomyelitis, acute suppurative and chronic granulomatous lesions with involvement of almost all organ systems. Fulminant sepsis is much more common and is associated with high mortality. Hence prompt recognition and early treatment is warranted. We report unusual presentations of urinary tract melioidosis in two diabetic men.
Insights
Melioidosis, a serious infection from Burkholderia pseudomallei, can affect many organs. This report highlights rare urinary tract cases in diabetic men, emphasizing the need for early diagnosis.
Area of Science:
- Infectious Diseases
- Microbiology
- Tropical Medicine
Background:
- Melioidosis is caused by Burkholderia pseudomallei, prevalent in tropical areas.
- The disease presents with diverse symptoms affecting multiple organ systems.
- Fulminant sepsis is common, leading to high mortality rates.
Observation:
- This study focuses on two diabetic men with unusual presentations of melioidosis.
- The cases specifically involve the urinary tract, a less common manifestation.
- Diabetes mellitus is a known risk factor for severe melioidosis.
Findings:
- The reported cases demonstrate atypical urinary tract involvement in melioidosis.
- These unusual presentations underscore the protean nature of Burkholderia pseudomallei infections.
- Prompt recognition of varied clinical signs is crucial for effective management.
Implications:
- Highlights the importance of considering melioidosis in diabetic patients with urinary symptoms, especially in endemic regions.
- Suggests that urinary tract melioidosis may be underdiagnosed.
- Emphasizes the need for broader diagnostic awareness among clinicians treating infectious diseases.
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