Related Experiment Videos
Severe nitrofurantoin lung disease resolving without the use of steroids
S Bhullar1, S M Lele, S Kraman
1Division of Pulmonary, Critical Care and Sleep, Department of Internal Medicine, University of Kentucky, Lexington, United Kingdom.
Abstract:
We report a case of an elderly woman who developed a severe, chronic pulmonary reaction to nitrofurantoin therapy that she had taken continuously for three years to prevent urinary tract infections. The patient was taking no other drug known to cause lung disease but the diagnosis was delayed by failure to recognize the association between nitrofurantoin and adverse drug reactions affecting the lung. When originally seen, the patient was unable to care for herself due to dyspnea. Bronchoscopy with biopsy ruled out other causes of her pulmonary disease. Immediate withdrawal of nitrofurantoin led to substantial, sustained improvement and disappearance of symptoms over several months without administration of corticosteroids. Nitrofurantoin toxicity should always be considered in any person taking that drug who develops bilateral infiltrates.
Related Concept Videos
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
COPD: Management Using Bronchodilators and Corticosteroids
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Cystic Fibrosis: Management
Sinus disease and chronic sinusitis...
Pneumothorax-II
Clinical Manifestations:
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories: