Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Premature ovarian failure.

Deepti Goswami1, Gerard S Conway

  • 1Department of Obstetrics and Gynaecology, Maulana Azad Medical College, New Delhi, India.

Hormone Research
|May 15, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Programmed death ligand-1 (PD-L1) expression in serous ovarian carcinoma with clinicopathological associations.

The Indian journal of medical research·2026
Same author

Unexpected Malignancy in Women Undergoing Surgery for Uterine Fibroids.

Cureus·2026
Same author

Complete Androgen Insensitivity Syndrome in a Phenotypic Female: The Role of Frozen Section in Assisting Diagnosis.

Cureus·2025
Same author

Prevalence and predictors of non-alcoholic fatty liver disease (NAFLD) and metabolic dysfunction-associated fatty liver disease (MAFLD) in Indian women with polycystic ovarian syndrome.

The journal of obstetrics and gynaecology research·2025
Same author

Mapping the anatomical and transcriptional landscape of early human fetal ovary development.

Scientific reports·2025
Same author

A Tiered Approach to Exome Sequencing Analysis in Early-Onset Primary Ovarian Insufficiency.

The Journal of clinical endocrinology and metabolism·2025
Same journal

Abstracts of the LWPES/ESPE 8th Joint Meeting Global Care in Paediatric Endocrinology, in collaboration with APEG, APPES, JSPE and SLEP. New York City, New York, USA. September 9-12, 2009.

Hormone research·2011
Same journal

Abstracts of the 47th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE). Istanbul, Turkey. September 20-23, 2008.

Hormone research·2011
Same journal

Abstracts of the 46th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE). Helsinki, Finland. June 27-30, 2007.

Hormone research·2011
Same journal

Genetic and pathogenetic aspects of Noonan syndrome and related disorders.

Hormone research·2009
Same journal

Response to growth hormone in short children with Noonan syndrome: correlation to genotype.

Hormone research·2009
Same journal

Growth hormone and the heart in Noonan syndrome.

Hormone research·2009
See all related articles

Premature ovarian failure (POF) is diagnosed by absent periods before 40 and high follicle-stimulating hormone. Management includes hormone therapy and successful infertility treatments like egg donation.

Area of Science:

  • Reproductive Endocrinology
  • Gynecology

Background:

  • Premature ovarian failure (POF) affects women before age 40.
  • Diagnosis relies on clinical and hormonal markers, excluding imaging.

Purpose of the Study:

  • To outline diagnostic criteria for POF.
  • To detail current and future management strategies for POF.

Main Methods:

  • Diagnosis based on amenorrhea and elevated follicle-stimulating hormone (FSH).
  • Workup includes screening for autoimmune conditions and karyotyping.
  • Exclusion of ovarian biopsy and ultrasound for diagnosis.

Main Results:

  • Amenorrhea before 40 with menopausal FSH levels confirms POF diagnosis.
  • Associated autoimmune disorders and karyotype abnormalities are key considerations.

Related Experiment Videos

  • Hormone replacement and assisted reproductive technologies are primary treatments.

    • Conclusions:

    • POF diagnosis is clinical and biochemical, not imaging-based.
    • Hormone replacement and assisted conception, particularly with donated oocytes, are effective management.
    • Future fertility preservation techniques like cryopreservation and in vitro maturation offer hope for specific patient groups.