Trauma associated with cardiac dysrhythmias: results from a large matched case-control study
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Published on: December 2, 2016
Rovshan M Ismailov1, Roberta B Ness, Carol K Redmond
1Bio Med Center for Population Health and Clinic Epidemiology, Brown University, Providence, RI 02940, USA. rovshani@yahoo.com
Insights
Blunt cardiac injury significantly increases the risk of cardiac dysrhythmia in hospitalized patients. This association was observed across different age groups, highlighting the importance of recognizing trauma-induced arrhythmias.
Area of Science:
- Cardiology
- Trauma Surgery
- Epidemiology
Background:
- Cardiac dysrhythmias are known complications of blunt cardiac and thoracic trauma.
- Previous reports were primarily based on case series.
- The association between blunt cardiac injury and dysrhythmia in a large population remained unclear.
Purpose of the Study:
- To determine if thoracic or blunt cardiac injury is associated with cardiac dysrhythmia.
- To analyze this association in a large, multistate hospitalized population.
Main Methods:
- Retrospective analysis of hospital discharge data from 986 hospitals across 33 states in 2001.
- Matched case-control study design, with controls matched by age.
- Identification of exposure (thoracic trauma, blunt cardiac injury) and outcome (cardiac dysrhythmias) using ICD-9-CM codes.
- Multivariate logistic regression analyses were performed.
Main Results:
- Blunt cardiac injury was a significant risk factor for cardiac dysrhythmia.
- Patients 50 years and younger with blunt cardiac injury had a fourfold increased risk.
- Patients 51 to 70 years old with blunt cardiac injury had a twofold increased risk, independent of confounders.
Conclusions:
- Blunt cardiac injury is a significant risk factor for developing cardiac dysrhythmia.
- Further longitudinal studies are recommended to better establish the trauma-dysrhythmia association.
Background:
Various cardiac dysrhythmias such as supraventricular and ventricular premature beats, supraventricular and ventricular paroxysmal tachycardia, atrial and ventricular fibrillation and atrial flutter have been reported in case series, as complications of blunt cardiac and thoracic trauma. The objective of this research was to determine whether thoracic or blunt cardiac injury is associated with cardiac dysrhythmia in a large multistate hospitalized population.
Methods:
Cases and matched (by age) controls were identified based on hospital discharge information that was collected from 986 acute general hospitals across 33 states in 2001. Both the exposure (thoracic trauma and blunt cardiac injury) and the outcome (cardiac dysrhythmias) were identified based on ICD-9-CM discharge diagnoses. Unadjusted and conditional adjusted (for gender, race, length of stay, and primary source of payment) multivariate logistic regression analyses were performed.
Results:
After adjusting for potential confounders, patients 50 years and younger diagnosed with blunt cardiac injury had a fourfold (95% confidence interval, 1.40-11.60) increase in the risk of cardiac dysrhythmia. Independent of potential confounding factors, discharge for blunt cardiac injury among patients 51 to 70 years old was associated with a twofold (95% confidence interval, 1.36-3.82) increased risk for cardiac dysrhythmia.
Conclusion:
Blunt cardiac injury was found to be a significant risk factor for cardiac dysrhythmia. Longitudinal studies are needed to better establish the association between trauma and cardiac dysrhythmias.
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