Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary changes in congenital syphilis.

R Austin1, R E Melhem

  • 1Department of Radiology, University of South Alabama, College of Medicine, Mobile.

Pediatric Radiology
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Digital and artificial intelligence-based screening for erosive tooth wear.

Journal of dentistry·2026
Same author

The interplay of saliva, erosion and attrition on enamel and dentine.

The Saudi dental journal·2022
Same author

Evaluation of implementation of risk management guidelines for carriers of pathogenic variants in mismatch repair genes: a nationwide audit of familial cancer clinics.

Familial cancer·2020
Same author

The role of citizen science in addressing grand challenges in food and agriculture research.

Proceedings. Biological sciences·2018
Same author

Medical conditions and erosive tooth wear.

British dental journal·2018
Same author

A two-centre experience of transanal total mesorectal excision.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2016

Congenital syphilis can cause persistent lung infiltrates in infants, even after antibiotic treatment. These findings suggest underlying issues like pulmonary immaturity and scarring.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Pulmonology

Background:

  • Congenital syphilis is a serious infection in newborns.
  • Pulmonary manifestations of congenital syphilis are not well-characterized.
  • Persistent lung abnormalities can impact infant health.

Purpose of the Study:

  • To describe pulmonary findings in infants with congenital syphilis.
  • To investigate the persistence of lung infiltrates post-treatment.
  • To explore potential causes of these persistent infiltrates.

Main Methods:

  • Retrospective review of seven infants diagnosed with congenital syphilis.
  • Analysis of clinical presentation, imaging, and pathological findings.
  • Correlation with treatment response and long-term outcomes.

Related Experiment Videos

Main Results:

  • Three of seven infants (43%) presented with diffuse pulmonary infiltrates.
  • Infiltrates persisted in these infants despite adequate antibiotic therapy for syphilis.
  • Pathological review suggested pulmonary immaturity, extramedullary hematopoiesis, and interstitial scarring as underlying causes.

Conclusions:

  • Diffuse pulmonary infiltrates are a significant finding in some infants with congenital syphilis.
  • Persistence of these infiltrates suggests non-infectious etiologies related to lung development and repair.
  • Further investigation into the long-term pulmonary sequelae of congenital syphilis is warranted.